DOD – Bone Marrow Failure Research Program (BMFRP) RD Award – Pre-Application
Well-being, Health and Biomedical Discovery
Deadlines
Academic Unit: Inquire with unit
Memorial Deadline: RIS Review not required for pre-application
External Deadline: Wednesday 7th, October 2026
Description
Resource Development Award
The BMFRP RDA supports the development of a multiomic atlas generated from well-annotated
human BMF samples, with omic data derived from marrow specimens. The resulting dataset
should serve as an open-access, durable resource to be shared with the BMF research and
clinical communities and is expected to facilitate further key discoveries that advance the
understanding of BMF diseases.
This funding opportunity invites proposals that will utilize previously stored viable human marrow
samples, and may include newly collected specimens, to generate comprehensive data
resources, such as genomic, transcriptomic, proteomic, metabolomic, and epigenomic data.
Proposals must include single-cell omic analyses of human marrow specimens as a
foundational component. Additional data types, such as serum metabolomic or other omic
modalities, may be incorporated only if they are accompanied by single-cell transcriptomic data
from the same specimens. Investigators are also encouraged to provide matched induced
pluripotent stem cell (iPSC) lines that correspond to the single-cell omic captures of the original
material, where available. Non-biospecimen data (such as patient reported outcomes) may be
integrated to enrich the biospecimen data. The goal is to support the collection, processing,
storage, and analysis of these biospecimens to create robust datasets for one or more BMF
diseases, thereby advancing the understanding of disease mechanisms and enabling future
research.
Award funds may be used for activities such as the collection and processing of biospecimens,
quality control, and the generation of multiomic data from both new and existing samples. While
the primary focus is on the creation of multiomic datasets, applicants are encouraged to
propose additional relevant omic analyses of marrow cell data that are clearly justified and
aligned with the needs of the BMF research community.
Pre-Application Due: October 7, 2026
Application Due: November 4, 2026
To view the funding opportunity announcement and submit a pre-application visit https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=727101