Pfizer – Relapsed/Refractory Multiple Myeloma – RFP

Pfizer’s GMG competitive grant program involves a publicly posted Request for Proposal (RFP) that provides detail regarding a general area of interest, sets timelines for review and approval, and uses an internal Pfizer review process to make final grant decisions. Organizations are invited to submit an application addressing the knowledge gaps as outlined in the specific RFP.

For all independent medical education grants, the grant requester (and ultimately the grantee) is responsible for the design, implementation, and conduct of the independent initiative supported by the grant. Pfizer must not be involved in any aspect of project development, nor the conduct of the independent education program.

Geographic Scope: North America & Europe

Clinical Area: Oncology-Hematology-Myeloma

Link to full RFP: Relapsed/Refractory Multiple Myeloma

Application Due Date:

This RFP has 2 timelines:
1. February 1, 2023 (only for urgent proposals that include symposia
held at fast-approaching congresses.) Planned decision notification
date February 17, 2023

2. March 1, 2023 (all other proposals.) Planned decision notification
date April 1, 2023

Please note the deadline is 23:59 Eastern Standard Time (e.g., New
York, GMT -5)

Specific Area of Interest: Projects that will be considered for Pfizer support will focus on increasing healthcare professional understanding of BCMA-directed therapies (BCMAxCD3 bi-specifics; BCMA-ADC; BCMA – CAR-T cells) in relapsed/refractory multiple myeloma, including:

• Mechanisms of action
• Available clinical data – efficacy insights and side effect profiles
• Overview of experiences and potential for sequencing of BCMA-directed treatments
• Clinical risk factors for the development of treatment-specific AEs
• Use of prognostic biomarkers (with focus on cytogenetics/GEP) in clinical practice
• Role of sBCMA on this therapeutic class
• Role of MRD in response assessment and therapy management
• Mechanisms of drug-resistance/loss of response with emerging treatments
• Therapy management